Cristian Vlad Zot explains in his book “Ketone Power” the cat chasing its tail game between hormones Leptin, Insulin and the enzyme LPL.

We’ve all heard the simple math explanation of calories consumed – calories burned = (weight loss OR weight gain).  But, this seems to be a bit oversimplified of an explanation.

There are several working parts that go together in this weight loss / weight gain spiral effect.  One place we’ve all been taught to look for answers to the fat problem is insulin.  Let’s take a look at a couple other factors that work in concert with insulin that cause you to keep packing on the pounds and what you can do about it.

LPL Accumulates FAT – But to Where?

LPL (Lipoprotein Lipase, enzyme) is an enzyme conducts of FAT.  LPL is either attached to fat ~ or muscle.  Any other scenarios are outside the realm of this discussion.

This is just my own personal conjecture of defining terms, however, LPL seems to almost be the fat version of insulin.  Insulin attaches to cells to get glucose into the cells to be used as energy.

LPL does the same thing.  It attaches to cells ~ fat cells.  And, muscle cells.

If LPL is attached to fat, then fat will conduct more fat.  If LPL is attached to muscle cells, then muscle cells will attract more fat.

If the muscles cells attract fat, then they turn the conducted fat into energy which is what you want.

Read this comprehensive overview of FAT here.

Insulin Increases LPL attached to FAT (BAD)

We already know the damages of insulin and its role in fat accumulation.  So, what do Insulin and LPL have to do with each other?

Studies show that higher levels of insulin promote LPL attachment to fat in the body and less to muscle causing – simply – more fat in the body.

However, with reduced amounts of Insulin, that same LPL is attached more to muscle tissues allowing fat to be used as energy.

So, in the absence of too much insulin, LPL is your friend.  LPL is what helps you metabolize fat as energy.

Take-away :

  • more insulin = more LPL attached to fat –> more FAT GAIN
  • less insulin = more LPL attached to muscle –> LESS fat GAIN more ENERGY

Leptin is Trying to Get Your Brain to Shut Off the Food Consumption

Leptin is a hormone produced by the fat in your body.  The blood sends it to the brain as a sort of role-call to say – “we, the fat, are all here and ready to serve.  You can stop taking in more food.  Stop eating!  Stop eating.”

Y’see ~ fat WANTS to be used as energy.

However, while leptin is trying to get the attention of the brain, just like people who are insulin resistant, people can also be leptin resistant.  Which means that leptin isn’t reaching the brain effectively – continuing the feeding frenzy – creating a fatter body.

And guess what profile of people tend to be Leptin resistant?  ~ if you said fat people, you are correct.  As a result this interferes with proper insulin production and function.  It’s one big cyclical fiasco.

If you’ve heard this 1 time, you’ve heard it a million times.  REDUCE your  CARBOHYDRATE intake!

The cycle looks something like this:

  •  If you are already fat and leptin resistant you are probably just going to get fatter.  That’s it – just one bullet point.


  • You stop feeding on all the carbs.  You can correct the leptin and insulin resistance problem in a fairly short period of time.

Carbs are the Culprit.

If you were thinking all-along that carbs must be the bad guy.  You were correct.  And, with a body that has been bent out-of-whack by carbs over many years, it’s even more important to get your carb intake in balance, to get your insulin, LPL, and Leptin levels and function working properly again.

NOTE: Leptin resistance is a sign for diagnosis of (T2D) type two diabetes.  Leptin resistance occurs years before insulin resistance which is when the major onslaught of diabetes occurs.

Action Plan

Reduce your carbs starting today.

Replace your carbs with some healthy fat such as Coconut Oil, 100% pure butter, and FISH.

All 3 of these fat sources play vital roles in your diet.

Become the NEW and Improved You.  Get a Head Start on Ketogenics Diet with Some Coconut Oil.  Put a Tablespoon of Coconut Oil in Your Morning Coffee and Be Full of Ketone Energy.